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Bruce and Prudence are deeply into therapy. Prudence's macho therapist is urging her to be more assertive while Bruce's wacky female therapist wants him to meet women by placing a personal ad. The lives of Bruce and Prudence intertwine. Bruce doesn't know how to handle poor nervous Prudence and Prudence doesn't know what to make of her unpredictable new boyfriend.

Set in Sunnyside, Queens in 1965, on the day Pope Paul VI visited New York City, the comedy features nuns, a political bombing, a GI headed for Vietnam, a zookeeper who dreams of making it big in Hollywood as a songwriter, and his wife Bananas, a schizophrenic destined for the institution that provides the play's title.

The play is a dark farce that satirises the Roman Catholic Church, social attitudes to death, and the integrity of the police force.